Research Scientist, Computational Enzyme Engineering

Added: 4/16/2021

REF: 9955

Contract: Permanent

Location: Cambridge, Massachusetts, United States

Company:

* Biotech company locate in Cambridge, MA

* Produce plant based ingredients

* Engineer microbes for production of different chemicals 


Job Title:

Research Scientist, Computational Enzyme Engineering

Responsibilities:

* Specialize in Machine Learning and Computational Protein design
* Have Deep experience in protein modeling or design
* Play a large part in their R&D team
* Design libraries to make enzymes more stable and soluble
* Predict enzyme mutations
* Assist with maintaining the computational hardware and software for bioengineering 
* Partner with the scientific team to discuss the results of your work
* Create predictive models for enzyme engineering with machine learning & deep learning

 

Required qualifications:

  • Ph.D. in Bioengineering, Biochemistry, Biostatistics, Chemical Engineering, Computer Science, or similar discipline
  • Experience with one or more of the protein modeling and design software such as Schrodinger, Rosetta, Discovery Studio, MOE, GROMACS, Amber, or NAMD
  • Experience with protein visualization software such as PyMOL
  • Statistics training and experience in data science methods (random forest, support vector machine, clustering, neural networks and deep learning)
  • Knowledge of database management systems such as Oracle/MySQL/PostgreSQL
  • Fluent in programming in a Linux environment using Python, other programming proficiency desirable

 

Preferred qualifications:

  • Experience using computational tools to improve enzyme activity and specificity
  • Experience developing prediction models with machine-learning/deep-learning techniques

Why Work Here:

  • Amazing Opportunity – There will be a lot of growth which will create opportunities for personal and professional advancement.
  • Accountability – You will be provided all of the resources you need to be successful and have the freedom to make it happen; the team will hold each other accountable through self progress
  • Passion – Everyone here loves what they do and they enjoy working with others who feel the same way. We love the challenge and hard work that come with working on the cutting edge.
  • Equity - You will be offered stock options on Day 1
  • Product - We have our own product that will be going to market

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